Stalled midway in putting on my trousers. I got up, drank coffee, took A shower, and now am gathering energy to finish dressing (IOW lying on my bed) and lamenting this headache. My brain hasn't been working very well this past week.
I wrote this at ten then neglected to publish :O
An NIH study regarding demyelination:
High-resolution real-time images show in mice how nerves may be damaged during the earliest stages of multiple sclerosis. The results suggest that the critical step happens when fibrinogen, a blood-clotting protein, leaks into the central nervous system and activates immune cells called microglia.
"We have shown that fibrinogen is the trigger," said Katerina Akassoglou, Ph.D., an associate investigator at the Gladstone Institute for Neurological Disease and professor of neurology at the University of California, San Francisco, and senior author of the paper published online in Nature Communications.
29 November 2012
27 November 2012
Lying in bed watching The Great Dictator. I had a grocery delivery this morning and so cleaned the fridge early as it was empty. The drivers have all been very nice. I always specify no substitutions as the subs I have received have been disastrous. The delivery website food seems to be quite limited, even so I always have unfilled items. This time it was toast bread, a load of fresh green beans, Walker's shortbread I was ordering as an xmas treat, and some of my grapefruit juice. I only order it when it is on sale, and I can count on them not bringing some of it. I ordered 10 half gallon bottles, and was brought 6 so I can't complain too much. If I order 6 they bring 4
My republicwifi phone should be coming soon. I then have a month to test it in case I want to send it back for a refund; if it works well I'll ditch my stupid landline and the new phone will be the same cost. It's a very middling phone but there is no phone choice at the moment, but it's leaps and bounds above the cheesey phone I have now (which doesn't even work out here in the boondocks).
I've had more energy so seized the opportunity to get back to exercising. I can't be faulted for not doing it when I'm on the ropes, low energy, after a fall, but it's hard to claw my way back and takes a lot of determination.
The model I'm working on is just being a beast. I made it, textured it, then realised it was too big. Texturing it is incredibly tough, so that made my heart sink. Then I made it smaller but accidentally uploaded the slightly bigger one and textured it. Then I uploaded the small one but inexplicably it had much higher land impact. I need to just back off a bit as as my brain is just not approaching this correctly.
I also watched 'Beyond the Sea' which is an over-the-top biopic about Bobby Darin, made by Kevin Spacey (who for years I thought was a television actor who had wandered into film). Over the top, down the hill, and into the next county. It wasn't unenjoyable if you could overlook its vanity-project aspect.
24 November 2012
'The government and party officials have what's called "tegong" food, e.g. specially designated land that grows food exclusively to feed them. The well-to-do import formula from Canada and the USA, or get their expatriate friends and family to mail to them. North American stores are overwhelmed by demand and had to set rations.
23 November 2012
I watched Afternoons with Margeuritte yesterday, which was enjoyable. Gerard Despardieu is fascinating to watch. Today I saw Patrik 1,5 which is a Swedish film that from the begining reminded me irresistaly of Edward Scissorhands (it was the neighborhood and how its dynamic was depicted that made me feel that). It was so-so, however.
20 November 2012
19 November 2012
11 and no juice.
10 pm still off :(
Ugh no trizzities since 6:45. It's now 9:18. Queuing this blog entry.
18 November 2012
17 November 2012
16 November 2012
Last Farewell to Groddle by Flask
14 November 2012
Glitch is closing :(
13 November 2012
Sunday's meeting to try to find Salazar by solving the portal problem.
12 November 2012
11 November 2012
WE PETITION THE OBAMA ADMINISTRATION TO:
Peacefully grant the State of North Carolina to withdraw from the United States and create its own NEW government
As the founding fathers of the United States of America made clear in the Declaration of Independence in 1776:
"When in the Course of human events, it becomes necessary for one people to dissolve the political bands which have connected them with another, and to assume among the powers of the earth, the separate and equal station to which the Laws of Nature and of Nature's God entitle them, a decent respect to the opinions of mankind requires that they should declare the causes which impel them to the separation."
"...Governments are instituted among Men, deriving their just powers from the consent of the governed, that whenever any Form of Government becomes destructive of these ends, it is the Right of the People to alter or abolish it, and institute new Government..."
Created: Nov 09, 2012
07 November 2012
06 November 2012
Imsorrymilo on reddit says:
According to scientific research cited by The Stranger, THC levels drop below the 5 nanograms-per-milliliter cutoff within a few hours of smoking. The 502 opposition drummed up this fear (and never cited any science) as a way to undermine the very core of the initiative's support.
05 November 2012
04 November 2012
Normal Spastin Gene Dosage Is Specifically Required for Axon Regeneration
Axon regeneration allows neurons to repair circuits after trauma; however, most of the molecular players in this process remain to be identified. Given that microtubule rearrangements have been observed in injured neurons, we tested whether microtubule-severing proteins might play a role in axon regeneration. We found that axon regeneration is extremely sensitive to levels of the microtubule-severing protein spastin. Although microtubule behavior in uninjured neurons was not perturbed in animals heterozygous for a spastin null allele, axon regeneration was severely disrupted in this background. Two types of axon regeneration—regeneration of an axon from a dendrite after proximal axotomy and regeneration of an axon from the stump after distal axotomy—were defective in Drosophila with one mutant copy of the spastin gene. Other types of axon and dendrite outgrowth, including regrowth of dendrites after pruning, were normal in heterozygotes. We conclude that regenerative axon growth is uniquely sensitive to spastin gene dosage.
Digestion products of the PH20 hyaluronidase inhibit remyelination
03 November 2012
It is a great day...We have lights, heat and telephone!!!!!!
01 November 2012